芳环的亲电取代反应及机制 5 Friedel-Crafts Acylation and Alkylation AKCl R一c-c|:+AKCl3 R-c=:+>R一c≡o aeV mI Rearrangement may occur in alkylation G⊙ RCl: ACl3 R AlCl
一、芳环的亲电取代反应及机制 5. Friedel-Crafts Acylation and Alkylation Rearrangement may occur in alkylation
芳环的亲电取代反应及机制 ●思考题:如何从苯合成正丁基苯?
一、芳环的亲电取代反应及机制 思考题：如何从苯合成正丁基苯？
二、取代基对芳环亲电取代反应的影响 o a study of the chemistry of aromatic compounds leads to deeper understanding of the effects of electronic and steric factors on reactivity, which will be of benefit in the further study of chemistry and biochemistry
二、取代基对芳环亲电取代反应的影响 A study of the chemistry of aromatic compounds leads to deeper understanding of the effects of electronic and steric factors on reactivity, which will be of benefit in the further study of chemistry and biochemistry
二、取代基对芳环亲电取代反应的影响 ●1. Experimental Facts CH3 CH, S CH3 HNO 2 Faster than nitration of beze ne NO2 ortho ard Br Br Br HNO3 NO 2 Slower than nitration of beze ne NO ortho NO 2 NO2 HN Slower than me ta nitration of beze ne NO
二、取代基对芳环亲电取代反应的影响 1. Experimental Facts: C H3 HNO3 C H3 N O2 C H3 N O2 ortho- paraFaster than nitration of bezene B r HNO3 B r N O2 B r N O2 ortho- paraSlower than nitration of bezene N O2 HNO3 N O2 Slower than nitration of bezene N O2 meta-