Biological Discrimination OH OH 生物鉴别 CH2一NH HO CHy (R)-(-)-epinephrine enzyme active site enzyme-substrate complex natural epinephrine 肾上腺素 used in medicine as a heart stimulant, OH OH vasoconstrictor,and bronchial relaxant. 白色到褐色之间的晶体 NH2一CH OH 化合物.用作心脏兴奋剂、 H 血管收缩剂和支气管肌 松弛剂 (S)-(+)-epinephrine unnatural epinephrine does not fit the enzyme's active site
Biological Discrimination 肾上腺素 used in medicine as a heart stimulant, vasoconstrictor, and bronchial relaxant. 白色到褐色之间的晶体 化合物.用作心脏兴奋剂、 血管收缩剂和支气管肌 松弛剂 生物鉴别
Me2N. Ph 0 darvon enzyme Darvon is a painkiller. Its enantiomer is an anticough agent. 手性药物chiral drugs Why to resolve the racemic mixtures to obtain the single enantiomer?
手性药物chiral drugs Why to resolve the racemic mixtures to obtain the single enantiomer?
Many pharmaceuticals are chiral! COOH Ibuprofen (Advil) Thalidomide: used as a sedative and anti-nausea drug
N N O O O O H H COOH H Many pharmaceuticals are chiral! Ibuprofen (Advil) Thalidomide: used as a sedative and anti-nausea drug * *
Other times,the different interaction of enantiomers with chiral biological molecules is serious. The two enantiomers of Thalidomide: beneficial sedative and anti-nausea drug Caused serious birth defects when taken by pregnant women!
N N O O O O H H N N O O O O H H Other times, the different interaction of enantiomers with chiral biological molecules is serious. * The two enantiomers of Thalidomide: beneficial sedative and anti-nausea drug * Caused serious birth defects when taken by pregnant women!
手性药物 Why to resolve the racemic mixtures to obtain the single enantiomer? 镇静 thalidomide 反应停
※Why to resolve the racemic mixtures to obtain the single enantiomer? thalidomide N N O O O O * 手性药物 反应停 镇静