Lactones (cyclic esters) HO OH + H2O 6-hydroxyvale ric acid δ-vale rolactone OH H2C OH Y-hydroxye nanthic acid Y-e nantholactone
Lactones (cyclic esters) OH O HO -hydroxyvaleric acid O O -valerolactone + H2 O OH O OH -hydroxyenanthic acid O O -enantholactone + H2 O
Gamma Hydroxybutyrate ⊕ HO CO2H HO CO>Na y-hydroxybutyric acid sodium 4-hydroxybutanoate or sodium y-hydroxybutyrate H3O (GHB) CNS depressant as of2000,Schedule I +H20 controlled substance If mixed with ROH,the depressant effects are enhanced Y-butyrolactone
Gamma Hydroxybutyrate HO CO2H HO CO2 N a or sodium -hydroxybutyrate sodium 4-hydroxybutanoate H3O + O O + H2O -butyrolactone (GHB) -hydroxybutyric acid CNS depressant as of 2000, Schedule I controlled substance If mixed with ROH, the depressant effects are enhanced
All Acid Derivatives can be Hydrolyzed (CH3)CHO OCH(CH) diisopropyl pimelate Hydrolysis H3O"or in base HO OH 2(CH3)2CHOH
All Acid Derivatives can be Hydrolyzed O O (CH3) 2 CHO OCH(CH3) 2 diisopropyl pimelate Hydrolysis H3 O + or in base O O HO OH + 2 (CH3) 2 CHOH
What are the 3 Hydrolysis Products? C-N(CH2CH3)2 H30 products are carboxylic acid(s) conjugate acid of the LGs Two hydrolyzable groups
What are the 3 Hydrolysis Products? O O C O N(CH2 CH3) 2 Two hydrolyzable groups H3 O + products are carboxylic acid(s) + conjugate acid of the LGs
0 C÷N(CH2CH2 CO2H H3O* OH HN(CH2CH3)2 HO
O O C O N(CH2 CH3) 2 H3O + OH CO2H + HN(CH2 C H3) 2 + HO O