Antibiotics Antibiotics are microbial meta bilites or synthetic analogs inspired by them that, in small doses, inhibit the growth and survival of microorganism In clinic the antibiotics are used to be antibacterial mainly, but in recent year, they can also be used for anti-cancer, anti viral, enzyme-inhibitors, and receptor-antagonist
Antibiotics Antibiotics are microbial metabilites or synthetic analogs inspired by them that,in small doses, inhibit the growth and survival of microorganism. In clinic the antibiotics are used to be antibacterial mainly,but, in recent year, they can also be used for anti-cancer,antiviral ,enzyme-inhibitors, and receptor-antagonist
Classification (According their structures) 1Beta- Lactam antibiotics(β-内酰胺类) 2 Tetracylines antibiotics(四环素类) 3 Aminoglycoside antibiotics(氨基糖甙类) 4 Macrolides antibiotics(大环内酯类) 5. Others
Classification (According their structures)： 1.Beta-Lactam antibiotics (β –内酰胺类) 2.Tetracylines antibiotics (四环素类) 3.Aminoglycoside antibiotics (氨基糖甙类) 4.Macrolides antibiotics (大环内酯类) 5. Others
Classification(According to their mechanism of actions 1. Inhibit the biosynthesis of bacterial cell walls(b-lactam) 2. React with cell membrances(polymycin) 3. Disturber with the biosynthesis of protein(aminoglycosides) Inhibit the replication and transcription of nucleonic acid (Nalicixic acid)
Classification (According to their mechanism of actions 1. Inhibit the biosynthesis of bacterial cell walls (β –Lactam) 2. React with cell membrances (Polymycin) 3. Disturber with the biosynthesis of protein (Aminoglycosides) 4. Inhibit the replication and transcription of nucleonic acid (Nalicixic acid)
(育哥素,头旭菌素 噬[ 中价纸胞浆膜细抱浆细胞壁扑制胞台成 察效必 (多粘團素、制幕 西、忙素B 抑制DNA台成 喹诺类 蛋彐历 影响叫酸代谢 (碳按类) 啊白蛋台成 愿啊RNA台成 (氨英甙员,坏 (甲哌力复素) 累类、德素 花素
1. B-Lactam Antibiotics * The group of antibiotics known as the B-lactams include penicillins, cephalosporins, monobactams and the carbapenems N N C-R CO COH Penicillin nucleus Cephalosporin nucleus HO R N 5C-Q-% 5-R SO.H COH Monobactam nucleus Carbapenem nucleus
1.*β –Lactam Antibiotics *The group of antibiotics known as the β-lactams include penicillins, cephalosporins, monobactams and the carbapenems