ATP thane Outer membrane F1) Freely permeable to Cristae smal olecules and ions Inner membrane Impermeable to moet aa moLecules and ions ineluding Ht Containes: Respiratory electron carriers (Complexes I-Iv) TP Ernnslocnsas △ TP synthase(F Other embrane transporters matrix Containe Pyruvate dehydrogen coMPlex Citric acact cele enzvmes HV Fatty acid B-crcidataon envies Aring neid oxi dation Ribstone DNA ribosomes Porin channels Many ather enzymes ATP ADP P Mg2+,Ca,K+ Manv sluble metabolic intermediates
线粒体的生物化学
The outer membrane is a relatively simple phospholipid bilayer, containing protein structures called porins[孔(道)蛋白] which render it permeable to molecules of about 10 kilodaltons or less(the size of the smallest proteins). lons, nutrient molecules, ATP, ADP, etc can pass through the outer membrane with ease
The outer membrane is a relatively simple phospholipid bilayer, containing protein structures called porins[孔(道)蛋白] which render it permeable to molecules of about 10 kilodaltons or less (the size of the smallest proteins). Ions, nutrient molecules, ATP, ADP, etc. can pass through the outer membrane with ease
The inner membrane is freely permeable only to oxygen, carbon dioxide, and water. Its structure is highly complex, including all of the complexes of the electron transport system, the ATp synthetase complex, and transport proteins. The wrinkles, or folds, are organized into lamellae ( layers, called the cristae(脊,嵴). The cristae greatly increase the total surface area of the inner membrane. The larger surface area makes room for many more of the above-named structures than if the inner membrane were shaped like the outer membrane
The inner membrane is freely permeable only to oxygen, carbon dioxide, and water. Its structure is highly complex, including all of the complexes of the electron transport system, the ATP synthetase complex, and transport proteins. The wrinkles, or folds, are organized into lamillae (layers), called the cristae (脊，嵴). The cristae greatly increase the total surface area of the inner membrane. The larger surface area makes room for many more of the above-named structures than if the inner membrane were shaped like the outer membrane
The membranes create two compartments. The intermembrane space, as implied, is the region between the inner and outer membranes It has an important role in the primary function of mitochondria. which is oxidative phosphorylation
The membranes create two compartments. The intermembrane space, as implied, is the region between the inner and outer membranes. It has an important role in the primary function of mitochondria, which is oxidative phosphorylation
The matrix contains the enzymes that are responsible for the citric acid cycle, B oxidation. aa oxidation and etc. The matrix also contains dissolved o2, h,o, co2, the recyclable intermediates that serve as energy shuttles, and much more. Because of the folds of the cristae, no part of the matrix is far from the inner membrane Therefore matrix components can quickly reach inner membrane complexes and transport proteins
The matrix contains the enzymes that are responsible for the citric acid cycle, - oxidation, AA oxidation and etc. The matrix also contains dissolved O2 , H2O, CO2 , the recyclable intermediates that serve as energy shuttles, and much more. Because of the folds of the cristae, no part of the matrix is far from the inner membrane. Therefore matrix components can quickly reach inner membrane complexes and transport proteins