Epidemic Cerebrospinal Meningitis Yuan Zhe MD Dept.Of Infectious Disease The First Affiliated Hospital Chongqing Medical University
Epidemic Cerebrospinal Meningitis Yuan Zhe MD Dept. Of Infectious Disease The First Affiliated Hospital Chongqing Medical University
DEFINITION 1.Epidemic cerebrospinal meningitis is acute infectious disease caused by meningococcus. 2.characteristics of ECM are fever, ■headache,vomiting, petechiae or ecchymosis and meningeal irritation signs.CSF is purulent
DEFINITION ◼ 1. Epidemic cerebrospinal meningitis is acute infectious disease caused by ◼ meningococcus. ◼ 2.characteristics of ECM are fever, ◼ headache, vomiting , petechiae or ecchymosis , and meningeal irritation signs. CSF is purulent
ETIOLOGY 1.Pathogen is Neisseria meningitidis (meningococcus);G diplococcus 2.Biological features: 2.1.The organism grow by incubation on blood,chocolate or trypticase soy agar in 5≈10%CO2,PH7.4~7.6; 2.2.The organism is susceptible to dry, heat chill and disinfectant;
ETIOLOGY ◼ 1.Pathogen is Neisseria meningitidis (meningococcus); G- diplococcus. ◼ 2.Biological features: ◼ 2.1.The organism grow by incubation ◼ on blood,chocolate or trypticase soy agar in 5~10%CO2,PH 7.4~7.6; ◼ 2.2.The organism is susceptible to dry, ◼ heat , chill and disinfectant;
ETIOLOGY 2.3.autolysis by autolysin in vitro; 3.The organism can be detected in patient's nasopharynx,blood,CSF, petechiae in skin; 4.Pathogenic factor:endotoxin
◼ 2.3. autolysis by autolysin in vitro; ◼ 3.The organism can be detected in patient’s nasopharynx, blood, CSF, petechiae in skin; ◼ 4.Pathogenic factor: endotoxin. ETIOLOGY