Malaria Yuan Zhe MD Dept.Infectious Disease 1st Affiliated Hospital Chongqing Medical University
Malaria Yuan Zhe MD Dept. Infectious Disease 1st Affiliated Hospital Chongqing Medical University
Definition *Malaria is a parasitosis caused by plasmodia. It is transmitted to human by the bite of mosquito. Clinical feature:cyclic chill,high fever profuse sweating.In chronic illness,there are anemia splenomegaly
Definition ❖Malaria is a parasitosis caused by plasmodia. ❖It is transmitted to human by the bite of mosquito. ❖Clinical feature: cyclic chill, high fever & profuse sweating. In chronic illness, there are anemia & splenomegaly
Etiology Causative organism:Plasmodia P.Vivax:tertian malaria >P.Malariae:quartan malaria >P.Falciparum:malignant malaria >P.Ovale:tertian malaria Pathogenicity:merozoite,malarial pigment products of metabolism
Etiology ❖Causative organism: Plasmodia ➢ P. Vivax: tertian malaria ➢ P. Malariae: quartan malaria ➢ P. Falciparum: malignant malaria ➢P. Ovale: tertian malaria ❖Pathogenicity: merozoite, malarial pigment & products of metabolism
Etiology Tachysporozoite *Bradysporozoite *Merozoite *Sporozoite *Parasitemia
Etiology ❖Tachysporozoite ❖Bradysporozoite ❖Merozoite ❖Sporozoite ❖Parasitemia
Etiology Tow period: >human-whole asexual reproduction >mosquito sexual parasitic stage Two host: >human-intermediate host >mosquito-final host *notes: >clinical symptoms:erythrocytic stage >relapse:exerythrocytic stage >infectivity:sporozoite
Etiology ❖Tow period: ➢human - whole asexual reproduction ➢mosquito - sexual parasitic stage ❖Two host: ➢human - intermediate host ➢mosquito - final host ❖notes: ➢clinical symptoms: erythrocytic stage ➢relapse: exerythrocytic stage ➢infectivity: sporozoite