Medical Genetics Molecular Disease
Molecular Disease Medical Genetics
Emphasis Molecular Disease Pathogenesis of Abnormal Hemoglobin Pathogenesis of Thalassemia 10
Emphasis ❖ Molecular Disease ❖ Pathogenesis of Abnormal Hemoglobin ❖ Pathogenesis of Thalassemia
*1902,Garrod AE the incidence of alkaptonuria: a study in clinical individuality *1948,Horlein H,Weber G g 1949,PaulingL Sickle cell anemia,a molecular disease. Science.110:543-548,1949
❖ 1902, Garrod AE the incidence of alkaptonuria: a study in clinical individuality ❖ 1949, Pauling L Sickle cell anemia, a molecular disease. Science. 110: 543-548, 1949. ❖ 1948, Hörlein H, Weber G
Molecular Disease A disease in which the manifestations are due to alterations in protein structure and quantity
Molecular Disease A disease in which the manifestations are due to alterations in protein structure and quantity
Structure of Hemoglobin
Structure of Hemoglobin