Aplastic Anemia ( AA Zhongshan Hospital, Fudan University Zou Shanhua
Aplastic Anemia (AA) Zhongshan Hospital ,Fudan University Zou Shanhua
Outline Bone marrow hematopoiesis failure led by chemicals radiation, biological factors and unknown etiology. The common clinical presentation is mild to severe pancytopenia
Outline Bone marrow hematopoiesis failure led by chemicals, radiation, biological factors and unknown etiology. The common clinical presentation is mild to severe pancytopenia
Epidemiology The incidence rate of Aa:074 per100000, AAA:0.14per1003000 cAA:060per100,000 Distribution: most AA patients are young and middle-aged people, male more than female
Epidemiology The incidence rate of AA :0.74 per 100,000， AAA : 0.14 per 100,000, CAA : 0.60 per 100,000. Distribution：most AA patients are young and middle-aged people, male more than female
Etiology Primary AA: unknown causes about 60-70% Secondary AA
Etiology Primary AA：unknown causes， about 60~70% Secondary AA
Etiology of Secondary AA Chemicals Drug: antibiotics, antineoplastic agent, NSAIDs Other chemicals benzene and benzene derivatives arsenic heavy metals insecticides
Etiology of Secondary AA Chemicals Drug: antibiotics, antineoplastic agent, NSAIDs Other chemicals: benzene and benzene derivatives, arsenic, heavy metals,insecticides