Hodgkins lymphoma 1. Presence of the distinctive neoplastic R-s cells and non-neoplastic cells usually greatly outnumber the tumor cells 2. Studies show that it is a tumor come of b lymphomacytes
Hodgkin’s lymphoma 1. Presence of the distinctive neoplastic R-S cells and non-neoplastic cells usually greatly outmumber the tumor cells. 2. Studies show that it is a tumor come of B lymphomacytes
Pato0 gical change of乩L Generral features Grossly Microscopically Classification Clinical course
Pathological change of HL Generral features Grossly Microscopically Classification Clinical course
Heneral features 1. a painless enlargenment of the lymph nodes 2. More often in upper half of the body cervical axillary, para-aortic) 3. Initially localized to a single peripheral lymph node region but orderly spread by contiguity nodes 4. Extranodal involvement uncommon
1. a painless enlargenment of the lymph nodes. General features 3. Initially localized to a single peripheral lymph node region but orderly spread by contiguity nodes. 4. Extranodal involvement uncommon. 2.More often in upper half of the body (cervical, axillary, para-aortic)
Grossly 1. The affected lymph node are enlarged, with a smooth surface, and the lymph node capsule is rarely breached 2. Lymph nodes conglutinate to be a fixed, nodular mass 3. Cut surface: white-gray fishy, yellowish necrosis
Grossly 1. The affected lymph node are enlarged, with a smooth surface, and the lymph node capsule is rarely breached . 2. Lymph nodes conglutinate to be a fixed, nodular mass. 3. Cut surface: white- gray ,fishy, yellowish necrosis
Microscopically Normal construction of lymph nodes were distroied 2. Characterized morphologically by the presence of distinctive neoplastic giant cells called Reed- Sternberg(Rs)cells; 3, The rs cells admixed with a variable infiltrate of reactive, nonmalignant inflammatory cells;
Microscopically 1. Normal construction of lymph nodes were distroied. 2. Characterized morphologically by the presence of distinctive neoplastic giant cells called ReedSternberg (RS) cells; 3. The RS cells admixed with a variable infiltrate of reactive, nonmalignant inflammatory cells;