1.2.2主动转运(active transport Concept:指物质逆浓度梯度或电位梯度的转运过程 Characteristics consumption of energy(消耗能量) ② helped by membrane protein(依靠膜蛋白质 的“帮助”) Ouphill against concentration or electrical gradient(逆电-化学梯度)
1.2.2 主动转运(active transport) Concept：指物质逆浓度梯度或电位梯度的转运过程 Characteristics： ① consumption of energy(消耗能量) ② helped by membrane protein(依靠膜蛋白质 的“帮助”) ③uphill against concentration or electrical gradient (逆电-化学梯度)
Classification: Primary active transport(原发性主动转运)： 能量直接来源于ATP.如：Na+-K+泵 Secondary active ransport(继发性主动转运)： 能量间接来源于ATP. Trans- Symport Antiport Carrier ported molecule ion Energy Coupled transport Active transport
Classification: Primary active transport (原发性主动转运): 能量直接来源于ATP.如：Na+-K+泵 Secondary active ransport (继发性主动转运): 能量间接来源于ATP
12.2.1 Primary active transport -Na+-K+ (Na+-K+Pump) 3Na*○ Extracellular fluid ○2K+ 3 Na+ ATP ADP P Cytosol 2K 3 5 Transporter Natis K+is released binds released, to cytosol. 3 Na'from K+binds. Cycle can cytosol. repeat. 2 4 Phosphorylation Dephosphorylation by ATP favors favors original conformational conformation. change
1.2.2.1 Primary active transport -Na+-K+泵 (Na+-K+ Pump)
N 膜外 心通道 膜内 Transport of sodium and p potassium ions through protein channals
Transport of sodium and potassium ions through protein channals
钠一钾泵 当Na]:个/K+]。个激活 分解ATP产生能量 2K+泵至细胞内；3Na+泵至细胞外 维持Na]。高、K]:高 原先的不均匀分布状态 钠-钾泵的这种活动还为其它一些物质转运的提供 了动力（如葡萄糖、氨基酸的吸收：Na+-载体-葡萄 糖、Na+-载体-氨基酸的复合体形式进行的联合转 运)
钠-钾泵的这种活动还为其它一些物质转运的提供 了动力（如葡萄糖、氨基酸的吸收：Na+-载体-葡萄 糖、Na+-载体-氨基酸的复合体形式进行的联合转 运）。 维持[Na+]o高、[K+] i高 原先的不均匀分布状态 2K+泵至细胞内;3Na+泵至细胞外 分解ATP产生能量 当[Na+] i↑/[K+] 钠-钾泵： o↑激活