PATHOGENY AND PATHOGENESIS(2) 2 alcoholic and overeat 3 obstruct of main pancreatic duct 4 diseases round the duodenum/ampullary region 5 postoperative pancreatitis and pancreatic trauma
6 PATHOGENY AND PATHOGENESIS(2) 2 alcoholic and overeat 3 obstruct of main pancreatic duct 4 diseases round the duodenum/ampullary region 5 postoperative pancreatitis and pancreatic trauma
PATHOGENY AND PATHOGENESIS(3) 6 infectious agents 7 medications: corticosteroids, estrogens 8 disorders of endocrinology and metabol ism: hyperparathyroidism, hyperlipidemia 9 others
7 PATHOGENY AND PATHOGENESIS(3) 6 infectious agents 7 medications: corticosteroids, estrogens 8 disorders of endocrinology and metabolism: hyperparathyroidism, hyperlipidemia 9 others:
PATHOGENY AND PATHOGENESIS(4) 6 inflammatory media theory In AP, the leukocytes that appear first in areas of inflammation are neutrophils, then macrophages, monocytes, lymphocytes and other cells. These cells can secrete a lot of inflammatory media (1)platelet activating factor, PAF 2)prostaglandins, PGs
8 PATHOGENY AND PATHOGENESIS(4) 6 inflammatory media theory In AP, the leukocytes that appear first in areas of inflammation are neutrophils, then macrophages, monocytes, lymphocytes, and other cells. These cells can secrete a lot of inflammatory media. (1) platelet activating factor, PAF (2)prostaglandins, PGs
PATHOGENY AND PATHOGENESIS(5) (3)leukotriens, LTS (4) kallikrein kinin systems, KKs (5)tumor necrosis factor-a, TNF-a (6)nitrogen monoxide, NO (7)complements 8)others: nuclear factor KB(NF-KB), toll like receptors(TLRs)
9 PATHOGENY AND PATHOGENESIS(5) (3) leukotriens, LTs (4) kallikrein kinin systems, KKS (5) tumor necrosis factor-, TNF- (6) nitrogen monoxide, NO (7) complements (8) others: nuclear factor B(NF- B), toll like receptors(TLRs)
DIAGNOSIS(1) Clinical characteristics 1 abdominal pain 2 fever 3 nausea and vomiting
10 DIAGNOSIS(1) • Clinical characteristics 1 abdominal pain 2 fever 3 nausea and vomiting